000 | 03091nam a2200289za04500 | ||
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001 | 17455 | ||
008 | 050703s2011 gw eng d | ||
020 | _a9783642142185 99783642142185 | ||
082 |
_a610.28 _b223 |
||
245 |
_aCellular and Biomolecular Mechanics and Mechanobiology _h[electronic resource] / _cedited by Amit Gefen. |
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300 |
_aX, 562 p. _bonline resource. |
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490 | _aStudies in Mechanobiology Tissue Engineering and Biomaterials | ||
490 |
_x-1868-2006 ; _v-4 |
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505 | _aPreface -- Fundamental concepts -- Cytoskeletal mechanics and cellular mechanotransduction: A molecular perspective -- Forces during cell adhesion and spreading: implications for cellular homeostasis -- The physical mechanical processes that shape tissues in the early embryo -- Mechanobiology of primary cilia -- Mechanical response of living cells to contacting shear force -- Experimental methods -- Microfabricated devices for studying cellular biomechanics and mechanobiology -- Nanotechnology usages for cellular adhesion and traction forces -- Global and local effects in three-dimensional biological hydrogels -- Global and local effects in three-dimensional biological hydrogels -- Global and local effects in three-dimensional biological hydrogels -- Biomechanical characterization of single chondrocytes -- Mechanics of airway smooth muscle cells and the response to stretch -- Computational modeling -- Biomechanical modelling of cells in mechanoregulation -- Finite element modeling of cellular mechanics experiments -- Multiscale computation of cytoskeletal mechanics during blebbing -- Mechanobiology and finite element analysis of cellular injury during microbubble flows -- Mathematical modeling of cell adhesion in tissue engineering using continuum models -- Cell-material communication: mechanosensing modelling for design in tissue engineering -- Mechanobiology in cancer -- Structure-mechanical property changes in nucleus arising from breast cancer -- Adhesion and signaling of tumor cells to leukocytes and endothelium in cancer metastasis -- Cellular mechanics of acute leukemia and chemotherapy. | ||
520 | _aThis book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads. | ||
650 |
_aEngineering. _996 |
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650 |
_aEngineering. _996 |
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650 |
_933764 _aCELL BIOLOGY |
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650 |
_933758 _aCYTOLOGY |
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650 |
_933509 _aBIOCHEMICAL ENGINEERING. |
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650 |
_933509 _aBIOCHEMICAL ENGINEERING. |
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700 |
_aGefen, Amit. _934257 |
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700 |
_eeditor. _934258 |
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710 |
_aSpringerLink (Online service) _9111 |
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856 |
_uhttp://springer.escuelaing.metaproxy.org/book/10.1007/978-3-642-14218-5 _yir a documento _qURL |
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942 |
_2ddc _cCF |
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999 |
_c14080 _d14080 |