000 03091nam a2200289za04500
001 17455
008 050703s2011 gw eng d
020 _a9783642142185 99783642142185
082 _a610.28
_b223
245 _aCellular and Biomolecular Mechanics and Mechanobiology
_h[electronic resource] /
_cedited by Amit Gefen.
300 _aX, 562 p.
_bonline resource.
490 _aStudies in Mechanobiology Tissue Engineering and Biomaterials
490 _x-1868-2006 ;
_v-4
505 _aPreface -- Fundamental concepts -- Cytoskeletal mechanics and cellular mechanotransduction: A molecular perspective -- Forces during cell adhesion and spreading: implications for cellular homeostasis -- The physical mechanical processes that shape tissues in the early embryo -- Mechanobiology of primary cilia -- Mechanical response of living cells to contacting shear force -- Experimental methods -- Microfabricated devices for studying cellular biomechanics and mechanobiology -- Nanotechnology usages for cellular adhesion and traction forces -- Global and local effects in three-dimensional biological hydrogels -- Global and local effects in three-dimensional biological hydrogels -- Global and local effects in three-dimensional biological hydrogels -- Biomechanical characterization of single chondrocytes -- Mechanics of airway smooth muscle cells and the response to stretch -- Computational modeling -- Biomechanical modelling of cells in mechanoregulation -- Finite element modeling of cellular mechanics experiments -- Multiscale computation of cytoskeletal mechanics during blebbing -- Mechanobiology and finite element analysis of cellular injury during microbubble flows -- Mathematical modeling of cell adhesion in tissue engineering using continuum models -- Cell-material communication: mechanosensing modelling for design in tissue engineering -- Mechanobiology in cancer -- Structure-mechanical property changes in nucleus arising from breast cancer -- Adhesion and signaling of tumor cells to leukocytes and endothelium in cancer metastasis -- Cellular mechanics of acute leukemia and chemotherapy.
520 _aThis book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads.
650 _aEngineering.
_996
650 _aEngineering.
_996
650 _933764
_aCELL BIOLOGY
650 _933758
_aCYTOLOGY
650 _933509
_aBIOCHEMICAL ENGINEERING.
650 _933509
_aBIOCHEMICAL ENGINEERING.
700 _aGefen, Amit.
_934257
700 _eeditor.
_934258
710 _aSpringerLink (Online service)
_9111
856 _uhttp://springer.escuelaing.metaproxy.org/book/10.1007/978-3-642-14218-5
_yir a documento
_qURL
942 _2ddc
_cCF
999 _c14080
_d14080