000 03843nam a2200349za04500
001 17555
008 050703s2011 gw eng d
020 _a9783642180958 99783642180958
082 _a610.28
_b223
245 _aBiomechanics and Mechanobiology of Aneurysms
_h[electronic resource] /
_cedited by Tim McGloughlin.
300 _aXIV, 424p. 152 illus.
_bonline resource.
490 _aStudies in Mechanobiology Tissue Engineering and Biomaterials
490 _x-1868-2006 ;
_v-7
505 _aEpidemiology Aetiology and Pathophysiology -- Advanced medical imaging in aneurysm diagnostics Biomechanics and Pathobiology of Aortic Aneurysm -- Computer-Aided Diagnosis of Abdominal Aortic Aneurysms -- New diagnostic approaches to AAA and Mechanical behavior of AAA tissue -- Fluid mechanics in -- Biomechanical aspects of Abdominal Aortic Aneurysm (AAA) and its risk of rupture: Fluid Structure Interaction (FSI) studies -- Computational analysis of displacement forces acting on endografts used to treat aortic aneurysms -- Experimental modelling of aneurysm behavior -- Endovascular treatment of AAA and long term outcomes -- Thoracic aortic aneurysms, clinical assessment and treatment -- Cranial aneurysms clinical assessment and treatment options -- Modelling Cerebral Aneurysm Evolution -- Biomechanical considerations of animal models of aneurysm.
520 _aCardiovascular disease is the leading cause of morbidity and premature death of modern era medicine. It is estimated that approximately 81 million people in the United States (US) currently have one or more of the many forms of cardiovascular disease, resulting in 1 in every 2.8 deaths, or 900,000 deaths per year. 40% of all deaths in Europe are a result of cardiovascular disease in people under the age of 75.รก Aneurysms form a significant portion of these cardiovascular related deaths and are defined as a permanent and irreversible localised dilation of a blood vessel greater than 50% of its normal diameter. Although aneurysms can form in any blood vessel, the more lethal aneurysms develop in the cranial arteries, and in the thoracic aorta and abdominal aorta. Frequently aneurysms are undetected and if left untreated may eventually expand until rupture with very high levels of morbidity and mortality. The biomechanics and mechanobiology of aneursymal diseases are not fully understood and this monograph aims to provide new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. The contributors to this volume bring together a unique blend of expertise in experimental, computational and tissue biomechanics relating to aneurysm behavior and enable the reader to gain a fresh understanding of key factors influencing aneurysm behavior and treatment. Biological risk factors such as tobacco smoking, sex, age, hypertension, family history and mechanobiological risk factors such as aneurysm geometry and shape as well as mechanical properties of the diseased tissues are considered in detail as are many of the diagnostic and treatment options.
650 _aEngineering.
_996
650 _91099
_aMATERIALS
650 _aEngineering.
_996
650 _933558
_aCONTINUUM MECHANICS AND MECHANICS OF MATERIALS
650 _934217
_aCARDIAC SURGERY
650 _934216
_aHUMAN PHYSIOLOGY
650 _934215
_aHEART
_xSURGERY
650 _934214
_aHUMAN PHYSIOLOGY
650 _933509
_aBIOCHEMICAL ENGINEERING.
650 _933509
_aBIOCHEMICAL ENGINEERING.
650 _933762
_aBIOMATERIALS
650 _933762
_aBIOMATERIALS
700 _aMcGloughlin, Tim.
_eEd.
_934218
710 _aSpringerLink (Online service)
_9111
856 _uhttp://springer.escuelaing.metaproxy.org/book/10.1007/978-3-642-18095-8
_yir a documento
_qURL
942 _2ddc
_cCF
999 _c14180
_d14180